USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: O75083 USC-OGP 2-DE database:  O75083 O75083 General information about the entry View entry in simple text format Entry name WDR1_HUMAN Primary accession number O75083 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1;. Gene name Name=WDR1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0325: pI=6.04; Mw=64774 SPOT OGP-0326: pI=6.10; Mw=64375 SPOT OGP-0327: pI=6.20; Mw=64375 SPOT OGP-0328: pI=6.30; Mw=63979 SPOT OGP-0331: pI=6.34; Mw=62806 SPOT OGP-0434: pI=5.89; Mw=39341 PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-0879: pI=6.22; Mw=60248 SPOT OGP-0880: pI=6.14; Mw=60085 SPOT OGP-0881: pI=6.33; Mw=60085 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1132: pI=6.61; Mw=65162 Cross-references UniProtKB/Swiss-Prot O75083; WDR1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name WDR1_HUMAN Primary accession number O75083 Secondary accession number(s) A8K6E9 A8MPU4 O75313 Q8N6E5 Q9UG05 Q9UG78 Q9UQE0 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 173) Name and origin of the protein Description RecName: Full=WD repeat-containing protein 1; AltName: Full=Actin-interacting protein 1; Short=AIP1; AltName: Full=NORI-1; Gene name Name=WDR1 Encoded on Name=WDR1 Keywords Acetylation; Actin-binding; Alternative splicing; Cell junction; Cell projection; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Phosphoprotein; Polymorphism; Reference proteome; Repeat; WD repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF020056; AAD05044.1; -; mRNA EMBL AF020260; AAD05045.1; ALT_SEQ; mRNA EMBL AB010427; BAA31855.2; -; mRNA EMBL AK291614; BAF84303.1; -; mRNA EMBL AC005674; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC093664; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL BC000201; AAH00201.1; -; mRNA EMBL BC002489; AAH02489.1; -; mRNA EMBL BC030541; AAH30541.1; -; mRNA EMBL AL050108; CAB43276.1; -; mRNA EMBL AL110208; CAB53674.2; -; mRNA CCDS CCDS54739.1; -. [O75083-3]; . CCDS CCDS54740.1; -. [O75083-1]; . PIR T13152; T13152; . RefSeq NP_005103.2; NM_005112.4. [O75083-3]; . RefSeq NP_059830.1; NM_017491.3. [O75083-1]; . UniGene Hs.128548; -; . UniGene Hs.713658; -; . ProteinModelPortal O75083; -; . SMR O75083; -; . BioGrid 115273; 101; . IntAct O75083; 29; . STRING 9606.ENSP00000427687; -; . iPTMnet O75083; -; . PhosphoSitePlus O75083; -; . SwissPalm O75083; -; . BioMuta WDR1; -; . OGP O75083; -; . REPRODUCTION-2DPAGE IPI00746165; -; . REPRODUCTION-2DPAGE O75083; -; . UCD-2DPAGE O75083; -; . EPD O75083; -; . PaxDb O75083; -; . PeptideAtlas O75083; -; . PRIDE O75083; -; . TopDownProteomics O75083-1; -. [O75083-1]; . Ensembl ENST00000382451; ENSP00000371889; ENSG00000071127. [O75083-3]; . Ensembl ENST00000382452; ENSP00000371890; ENSG00000071127. [O75083-1]; . Ensembl ENST00000499869; ENSP00000427687; ENSG00000071127. [O75083-1]; . Ensembl ENST00000502702; ENSP00000426725; ENSG00000071127. [O75083-3]; . GeneID 9948; -; . KEGG hsa:9948; -; . UCSC uc032tcf.2; human. [O75083-1]; . CTD 9948; -; . DisGeNET 9948; -; . GeneCards WDR1; -; . HGNC HGNC:12754; WDR1; . HPA CAB020804; -; . HPA HPA036434; -; . HPA HPA058132; -; . MIM 604734; gene; . neXtProt NX_O75083; -; . OpenTargets ENSG00000071127; -; . PharmGKB PA37358; -; . eggNOG KOG0318; Eukaryota; . eggNOG ENOG410XQN1; LUCA; . GeneTree ENSGT00390000009416; -; . HOVERGEN HBG000780; -; . InParanoid O75083; -; . OMA WDVGANS; -; . OrthoDB EOG091G03SZ; -; . PhylomeDB O75083; -; . TreeFam TF300821; -; . Reactome R-HSA-114608; Platelet degranulation; . SignaLink O75083; -; . ChiTaRS WDR1; human; . GeneWiki WDR1; -; . GenomeRNAi 9948; -; . PRO PR:O75083; -; . Proteomes UP000005640; Chromosome 4; . Bgee ENSG00000071127; -; . CleanEx HS_WDR1; -; . ExpressionAtlas O75083; baseline and differential; . Genevisible O75083; HS; . GO GO:0042643; C:actomyosin; actin portion; IBA:GO_Central GO GO:0042995; C:cell projection; IEA:UniProtKB-KW; . GO GO:0005911; C:cell-cell junction; IDA:UniProtKB; . GO GO:0030864; C:cortical actin cytoskeleton; IBA:GO_Central; . GO GO:0005829; C:cytosol; IDA:HPA; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0002102; C:podosome; IEA:UniProtKB-SubCell; . GO GO:0051015; F:actin filament binding; ISS:UniProtKB; . GO GO:0030043; P:actin filament fragmentation; IEA:Ensembl; . GO GO:0043297; P:apical junction assembly; IDA:UniProtKB; . GO GO:0030865; P:cortical cytoskeleton organization; IEA:Ensembl; . GO GO:0042247; P:establishment of planar polarity of follicular epithelium; IEA:Ensembl; . GO GO:0040011; P:locomotion; IBA:GO_Central; . GO GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IDA:UniProtKB; . GO GO:0002446; P:neutrophil mediated immunity; IEA:Ensembl; . GO GO:1990266; P:neutrophil migration; IEA:Ensembl; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0030220; P:platelet formation; IEA:Ensembl; . GO GO:0030836; P:positive regulation of actin filament depolymerization; IBA:GO_Central; . GO GO:0030834; P:regulation of actin filament depolymerization; IDA:UniProtKB; . GO GO:0008360; P:regulation of cell shape; IEA:Ensembl; . GO GO:0048713; P:regulation of oligodendrocyte differentiation; IEA:Ensembl; . GO GO:0060307; P:regulation of ventricular cardiac muscle cell membrane repolarization; IEA:Ensembl; . GO GO:0045214; P:sarcomere organization; IBA:GO_Central; . GO GO:0007605; P:sensory perception of sound; TAS:ProtInc; . Gene3D 2.130.10.10; -; 3; . InterPro IPR020472; G-protein_beta_WD-40_rep; . InterPro IPR011045; N2O_reductase_N; . InterPro IPR015943; WD40/YVTN_repeat-like_dom; . InterPro IPR001680; WD40_repeat; . InterPro IPR019775; WD40_repeat_CS; . InterPro IPR017986; WD40_repeat_dom; . Pfam PF00400; WD40; 4; . PRINTS PR00320; GPROTEINBRPT; . SMART SM00320; WD40; 11; . SUPFAM SSF50974; SSF50974; 1; . SUPFAM SSF50978; SSF50978; 1; . PROSITE PS00678; WD_REPEATS_1; 1; . PROSITE PS50082; WD_REPEATS_2; 5; . PROSITE PS50294; WD_REPEATS_REGION; 1; .

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